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ctcf  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc ctcf
    The extraction process and proposed mechanisms for GPEVs in treating UVB-induced Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. UVB radiation triggers the up-regulation of STING, activating the <t>TBK1-CTCF</t> pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.
    Ctcf, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/%CE%B1+ctcf/pmc13050126-128-7-9?v=Cell+Signaling+Technology+Inc
    Average 86 stars, based on 1 article reviews
    ctcf - by Bioz Stars, 2026-08
    86/100 stars

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    1) Product Images from "Gynostemma pentaphyllum -derived extracellular vesicles alleviate skin aging by destabilizing STING"

    Article Title: Gynostemma pentaphyllum -derived extracellular vesicles alleviate skin aging by destabilizing STING

    Journal: Bioactive Materials

    doi: 10.1016/j.bioactmat.2026.03.010

    The extraction process and proposed mechanisms for GPEVs in treating UVB-induced Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. UVB radiation triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.
    Figure Legend Snippet: The extraction process and proposed mechanisms for GPEVs in treating UVB-induced Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. UVB radiation triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.

    Techniques Used: Extraction, Derivative Assay, Isolation, Purification



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    Image Search Results


    The extraction process and proposed mechanisms for GPEVs in treating UVB-induced Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. UVB radiation triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.

    Journal: Bioactive Materials

    Article Title: Gynostemma pentaphyllum -derived extracellular vesicles alleviate skin aging by destabilizing STING

    doi: 10.1016/j.bioactmat.2026.03.010

    Figure Lengend Snippet: The extraction process and proposed mechanisms for GPEVs in treating UVB-induced Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. UVB radiation triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.

    Article Snippet: The primary antibodies used included γ-H2AX and CTCF (1:1,000, Cell Signaling), p21 and STING (diluted 1:1,000, Cell Signaling).

    Techniques: Extraction, Derivative Assay, Isolation, Purification